Upregulation of CD9 in ovarian cancer is related to the induction of TNF-a gene expression and constitutive NF-kB activation
نویسندگان
چکیده
Jae Ryoung Hwang, Kiwon Jo, Yoonna Lee, Byung-Jun Sung, Young Woo Park and Je-Ho Lee Molecular Therapy Research Center, Sungkyunkwan University, Samsung Medical Center, 50 Ilwon-dong, Kangnamgu, Seoul 135-710, Korea, Therapeutic Antibody Research Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon 305-806, Korea and Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
منابع مشابه
Upregulation of CD9 in ovarian cancer is related to the induction of TNF-α gene expression and constitutive NF-κB activation.
Ovarian cancer is a gynecological cancer with a high death rate. We utilized global gene expression profiles of ovarian carcinomas obtained by complementary DNA (cDNA) microarray to identify ovarian cancer-specific proteins. CD9 was upregulated in ovarian carcinomas, and overexpression of the CD9 protein was detected in ovarian carcinomas by immunohistochemistry. CD9 was also overexpressed in s...
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تاریخ انتشار 2011